Article
The Salmonella type-3 secretion system-1 and flagellar motility influence the neutrophil respiratory burst.
PloS one - 1 Jan 2018
Westerman Trina L, Bogomolnaya Lydia, Andrews-Polymenis Helene L, Sheats M Katherine, Elfenbein Johanna R
Abstract excerpt
Neutrophils are innate immune response cells designed to kill invading microorganisms. One of the mechanisms neutrophils use to kill bacteria is generation of damaging reactive oxygen species (ROS) via the respiratory burst. However, during enteric salmonellosis, neutrophil-derived ROS actually facilitates Salmonella expansion and survival in the gut. This seeming paradox led us to hypothesize that Salmonella may...
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