Article
The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers.
Proceedings of the National Academy of Sciences of the United States of America - 23 Oct 2018
Elbau Immanuel G, Brücklmeier Benedikt, Uhr Manfred, Arloth Janine, Czamara Darina, Spoormaker Victor I, Czisch Michael, Stephan Klaas Enno, Binder Elisabeth B, Sämann Philipp G
Abstract excerpt
Ample evidence links dysregulation of the stress response to the risk for psychiatric disorders. However, we lack an integrated understanding of mechanisms that are adaptive during the acute stress response but potentially pathogenic when dysregulated. One mechanistic link emerging from rodent studies is the interaction between stress effectors and neurovascular coupling, a process that adjusts cerebral blood...
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