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Article

Effects of Sunitinib and Other Kinase Inhibitors on Cells Harboring a PDGFRB Mutation Associated with Infantile Myofibromatosis.

International journal of molecular sciences - 1 Sept 2018

Sramek Martin, Neradil Jakub, Macigova Petra, Mudry Peter, Polaskova Kristyna, Slaby Ondrej, Noskova Hana, Sterba Jaroslav, Veselska Renata

Abstract excerpt

Infantile myofibromatosis represents one of the most common proliferative fibrous tumors of infancy and childhood. More effective treatment is needed for drug-resistant patients, and targeted therapy using specific protein kinase inhibitors could be a promising strategy. To date, several studies have confirmed a connection between the p.R561C mutation in gene encoding platelet-derived growth factor receptor beta...

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Identifiers

PMID: 30200486
DOI: 10.3390/ijms19092599
PMCID: PMC6163232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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