Case report: rapid and durable response to PDGFR targeted therapy in a child with refractory multiple infantile myofibromatosis and a heterozygous germline mutation of the PDGFRB gene

Abstract excerpt

BACKGROUND: Infantile myofibromatosis belongs to a family of soft tissue tumors. The majority of these tumors have benign behavior but resistant and malignant courses are known, namely in tumors with visceral involvement. The standard of care is surgical resection. Observations suggest that low dose chemotherapy is beneficial. The treatment of resistant or relapsed patients with multifocal disease remains...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital Diaphragmatic Hernia Studies
• Share to IgG4-Related and Inflammatory Diseases
• Share to Soft tissue tumor case studies