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Article

A novel SOCS5/miR‐18/miR‐25 axis promotes tumorigenesis in liver cancer

7 Sept 2018

Abstract excerpt

The role of miRNAs with tumor suppressive activity in liver cancer has been well studied. However, little is known about potential oncomiRs in HCC. In our study, we conducted a systematic evaluation of candidate oncomiRs and found that upregulation of miR-18a and miR-25 in HCC was associated with poor patient survival and promoted proliferation in HCC cell lines. These two miRNAs belong to the polycistronic...

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PMID: 30191950
DOI: 10.1002/ijc.31857

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