Article
Predicting IDH genotype in gliomas using FET PET radiomics.
Scientific reports - 6 Sept 2018
Lohmann Philipp, Lerche Christoph, Bauer Elena K, Steger Jan, Stoffels Gabriele, Blau Tobias, Dunkl Veronika, Kocher Martin, Viswanathan Shivakumar, Filss Christian P, Stegmayr Carina, Ruge Maximillian I, Neumaier Bernd, Shah Nadim J, Fink Gereon R, Langen Karl-Josef, Galldiks Norbert
Abstract excerpt
Mutations in the isocitrate dehydrogenase (IDH mut) gene have gained paramount importance for the prognosis of glioma patients. To date, reliable techniques for a preoperative evaluation of IDH genotype remain scarce. Therefore, we investigated the potential of O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET radiomics using textural features combined with static and dynamic parameters of FET uptake for noninvasive...
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