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Article

Bovine Neonatal Pancytopenia-Associated Alloantibodies Recognize Individual Bovine Leukocyte Antigen 1 Alleles.

Frontiers in immunology - 1 Jan 2018

Kasonta Rahel, Mauritz Jacqueline, Spohr Christina, Sauter-Louis Carola, Duchow Karin, Cussler Klaus, Holsteg Mark, Bastian Max

Abstract excerpt

Bovine neonatal pancytopenia (BNP) was a vaccine-induced alloimmune disease observed in young calves and characterized by hemorrhages, pancytopenia, and severe destruction of the hematopoietic tissues. BNP was induced by alloreactive maternal antibodies present in the colostrum of certain cows vaccinated with a highly adjuvanted vaccine against bovine viral diarrhea. Bioprocess impurities, originating from the...

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Identifiers

PMID: 30154800
DOI: 10.3389/fimmu.2018.01902
PMCID: PMC6102493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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