Article
Analysis of gene polymorphisms associated with K ion circulation in the inner ear of patients susceptible and resistant to noise-induced hearing loss.
Annals of human genetics - 1 Jul 2009
Pawelczyk Malgorzata, Van Laer Lut, Fransen Erik, Rajkowska Elzbieta, Konings Annelies, Carlsson Per-Inge, Borg Erik, Van Camp Guy, Sliwinska-Kowalska Mariola
Abstract excerpt
Noise-induced hearing loss (NIHL) is one of the leading occupational health risks in industrialized countries. It results from an interaction between environmental and genetic factors, however the nature of the genetic factors contributing to NIHL has not yet been clarified. Here, we investigated whether genetic variations in 10 genes putatively involved in the potassium recycling pathway in the inner ear may...
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