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Article

Evidence for the importance of the "genotype" theory in alcohol seeking behavior: a commentary.

Alcohol and drug research - 1 Jan 2000

Blum K, Wallace J E, Briggs A H, Trachtenberg M C

Abstract excerpt

Consensus of the literature points towards a neuropsychogenetic model of alcoholism. Evidence in both animals and humans tends to support the proposed "genotype" theory of alcohol-seeking behavior, whereby a predisposition to alcohol preference may be mediated in part by either innate (genetic) or environmentally (stress and/or alcohol) induced brain opioid peptide dysfunction. Potential therapeutic rationale...

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PMID: 3015159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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