Article
Adiponectin Receptor gene Polymorphisms are Associated with Kidney Function in Elderly Japanese Populations.
Journal of atherosclerosis and thrombosis - 1 Apr 2019
Kobayashi Hiroki, Otsuka Hiromasa, Yanai Mitsuru, Hara Motohiko, Hishiki Mikano, Soma Masayoshi, Abe Masanori
Abstract excerpt
AIM: Adiponectin exhibits its biological effects through adiponectin receptors (AdipoR1 and AdipoR2), which are distributed in the kidneys, and activation of those receptors could prevent or ameliorate diabetic nephropathy. This study aimed to evaluate the associations between AdipoR single nucleotide polymorphisms (SNPs) and kidney function in an elderly Japanese population. METHODS: A total of 271 elderly...
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