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Article

A second post-transcriptional trans-activator gene required for HTLV-III replication.

Nature - 1 Jan 2000

Sodroski J, Goh W C, Rosen C, Dayton A, Terwilliger E, Haseltine W

Abstract excerpt

Evidence is provided for the existence of a seventh gene in the genome of human T-lymphotropic virus type III/lymphadenopathy-associated virus. The gene is necessary for replication and acts post-transcriptionally to relieve negative regulation of the messenger RNA for the virion capsid and envel...

Topics

Cell Line
DNA Replication
DNA Restriction Enzymes
Deltaretrovirus
Genes
Genes, Viral
Humans
Lymphocytes
Mutation
Plasmids
Protein Biosynthesis
RNA Processing, Post-Transcriptional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Transfection

Viral Envelope Proteins

Virus Replication

Source

Identifiers

PMID: 3012355
DOI: 10.1038/321412a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3012355-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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