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Article

Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes.

Scientific reports - 17 Aug 2018

Sandholm Niina, Haukka Jani K, Toppila Iiro, Valo Erkka, Harjutsalo Valma, Forsblom Carol, Groop Per-Henrik

Abstract excerpt

Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. Despite substantial estimated heritability, only variants in the GLRA3 gene have been genome-wide significantly associated (p-value < 5 × 10-8) with diabetic albuminuria, in Finnish individuals with type 1 diabetes; However, replication attempt in non-Finnish Europeans with type 1 diabetes showed...

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Source

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Identifiers

PMID: 30120300
DOI: 10.1038/s41598-018-29211-1
PMCID: PMC6098108

Genes

GLRA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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