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The association between genetic risk score and blood pressure is modified by coffee consumption: Gene-diet interaction analysis in a population-based study.

Clinical nutrition (Edinburgh, Scotland) - 1 Aug 2019

Miranda Andreia Machado, Steluti Josiane, Norde Marina Maintinguer, Fisberg Regina Mara, Marchioni Dirce Maria

Abstract excerpt

BACKGROUND & AIM: Recent genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) that are associated with high blood pressure (BP). However, whether coffee consumption interacts with the genetic variants related to BP is yet unclear. Thus, this study aimed to investigate whether the association between genetic risk core (GRS) and blood pressure was modified by usual coffee...

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Identifiers

PMID: 30119983
DOI: 10.1016/j.clnu.2018.07.033

Genes

DBP
CPLX3
MTHFR
ULK3

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