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Article

Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.

Molecular reproduction and development - 1 Aug 2018

El Khouri Elma, Whitfield Marjorie, Stouvenel Laurence, Kini Archana, Riederer Brigitte, Lores Patrick, Roemermann Dorothee, di Stefano Gabriella, Drevet Joël R, Saez Fabrice, Seidler Ursula, Touré Aminata

Abstract excerpt

Members of the solute carrier 26 (SLC26) family have emerged as important players in mediating anions fluxes across the plasma membrane of epithelial cells, in cooperation with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. Among them, SLC26A3 acts as a chloride/bicarbonate exchanger, highly expressed in the gastrointestinal, pancreatic and renal tissues. In humans, mutations in...

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Identifiers

PMID: 30118583
DOI: 10.1002/mrd.23055

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.PMID 30118583Read ↗

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