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Article

Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) Superfamily

31 Jul 2018

Abstract excerpt

The mef(A) gene was originally identified as the resistance determinant responsible for type M resistance to macrolides, a phenotype frequently found in clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes. MefA was defined as a secondary transporter of the Major Facilitator Superfamily driven by proton-motive force. However, when characterizing the mef(A)-carrying elements Tn1207.1 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30108557
DOI: 10.3389/fmicb.2018.01670

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Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) SuperfamilyPMID 30108557Read ↗

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