Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrolide Efflux in <i>Streptococcus pneumoniae</i> Is Mediated by a Dual Efflux Pump ( <i>mel</i> and <i>mef</i> ) and Is Erythromycin Inducible

27 Sept 2005

Abstract excerpt

Macrolide resistance in Streptococcus pneumoniae due to efflux has emerged as an important worldwide clinical problem over the past decade. Efflux is mediated by the genes of the genetic element mega (macrolide efflux genetic assembly) and related elements, such as Tn1207.1. These elements contain two adjacent genes, mef (mefE or mefA) and the closely related mel gene (msrA homolog), encoding a proton motive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Pneumocystis jirovecii pneumonia detection and treatment
Share to Pneumonia and Respiratory Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16189099
DOI: 10.1128/aac.49.10.4203-4209.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrolide Efflux in <i>Streptococcus pneumoniae</i> Is Mediated by a Dual Efflux Pump ( <i>mel</i> and <i>mef</i> ) and Is Erythromycin InduciblePMID 16189099Read ↗

Macrolide Efflux Genes <i>mef</i> (A) and <i>mef</i> (E) Are Carried by Different Genetic Elements in <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Inducible Mega-Mediated Macrolide Resistance Confers Heteroresistance in Streptococcus pneumoniaeSemantic proximity Read ↗

Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) SuperfamilySemantic proximity Read ↗

Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides.Semantic proximity Read ↗

Molecular Characterization of Pneumococci with Efflux-Mediated Erythromycin Resistance and Identification of a Novel mef Gene Subclass, mef (I)Semantic proximity Read ↗

Macrolide Resistance in Streptococcus pneumoniae.Semantic proximity Read ↗

Characterization and Prevalence of MefA, MefE, and the Associated msr (D) Gene in Streptococcus pneumoniae Clinical IsolatesSemantic proximity Read ↗

Characterization of a Genetic Element Carrying the Macrolide Efflux Gene <i>mef</i> (A) in <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Beyond Ribosomal Mutations: Identification of MPN_080 as a Novel ATPase-Dependent Determinant of Macrolide Resistance in <em>Mycoplasma pneumoniae</em>Semantic proximity Read ↗

Tn 2009 , a Tn 916 -Like Element Containing mef (E) in Streptococcus pneumoniaeSemantic proximity Read ↗

Mechanisms of macrolide resistance in clinical pneumococcal isolates in a university hospital, Ankara, Turkey.Semantic proximity Read ↗

mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.