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Article

Adrenocortical carcinoma (ACC): When and why should we consider germline testing?

Presse medicale (Paris, France : 1983) - 1 Jan 2000

Petr Elisabeth Joye, Else Tobias

Abstract excerpt

Adrenocortical carcinoma (ACC), particularly when occurring during childhood, has been a traditional component of the tumor spectrum of Li-Fraumeni syndrome. Recent research has defined a significant risk increase of ACC with other familial cancer syndromes, such as Lynch syndrome and multiple endocrine neoplasia. ACC patients can serve as index patients for a new family diagnosis of a hereditary syndrome,...

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Identifiers

PMID: 30104051
DOI: 10.1016/j.lpm.2018.07.004

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