Article
Association of adrenocortical carcinoma with familial cancer susceptibility syndromes.
Molecular and cellular endocrinology - 31 Mar 2012
Else Tobias
Abstract excerpt
Our knowledge about inherited susceptibility to adrenocortical carcinoma (ACC) almost exclusively stems from experiences with familial cancer susceptibility syndromes, which are caused by single gene mutations (e.g. Li-Fraumeni syndrome (LFS)). Population-based studies are largely unavailable. ACC diagnosed during childhood is known to be commonly part of hereditary cancer syndromes. Childhood ACC is part of the...
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