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Association between the MVK rs2287218 SNP and the risk of coronary heart disease and ischemic stroke: A case-control study.

Bioscience trends - 19 Sept 2018

Wang Duo-Shun, Yin Rui-Xing, Li Kai-Guang, Lu Li, Su Yuan, Yan Rong-Qin

Abstract excerpt

The association between the mevalonate kinase gene (MVK) single nucleotide polymorphism (SNP) and serum lipid levels has been detected in several previous genome-wide association studies, but the results are inconsistent. In addition, it is still unclear whether the loci indentified exert the similar effect on the susceptibility of coronary heart disease (CHD) or ischemic stroke (IS). Therefore, the present study...

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PMID: 30101835
DOI: 10.5582/bst.2018.01146

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MVK

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