Article
Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect.
Investigative ophthalmology & visual science - 1 Aug 2018
Shaaban Sherin, MacKinnon Sarah, Andrews Caroline, Staffieri Sandra E, Maconachie Gail D E, Chan Wai-Man, Whitman Mary C, Morton Sarah U, Yazar Seyhan, MacGregor Stuart, Elder James E, Traboulsi Elias I, Gottlob Irene, Hewitt Alex W, Hunter David G, Mackey David A, Engle Elizabeth C
Abstract excerpt
Purpose: To identify genetic variants conferring susceptibility to esotropia. Esotropia is the most common form of comitant strabismus, has its highest incidence in European ancestry populations, and is believed to be inherited as a complex trait. Methods: White European American discovery cohorts with nonaccommodative (826 cases and 2991 controls) or accommodative (224 cases and 749 controls) esotropia were...
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