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Article

Drug resistance among patients who acquired HIV infection in a preexposure prophylaxis trial.

AIDS (London, England) - 23 Oct 2018

Delaugerre Constance, Rodriguez Christophe, Capitant Catherine, Nere Marie-Laure, Mercier-Darty Mélanie, Carette Diane, Pialoux Gilles, Cotte Laurent, Charreau Isabelle, Molina Jean-Michel

Abstract excerpt

BACKGROUND: The IPERGAY ANRS trial showed that on-demand preexposure prophylaxis (PrEP) with tenofovir (TDF) and emtricitabine (FTC) was highly effective in preventing HIV infection among highly exposed MSM. Here, we analyzed drug resistance-associated mutations (RAMs) among all participants who acquired HIV infection during this trial. METHODS: Resistance was analyzed on frozen plasma at the time of HIV...

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Identifiers

PMID: 30096070
DOI: 10.1097/QAD.0000000000001960

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