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Article

Low clinical impact of HIV drug resistance mutations in oral pre-exposure prophylaxis: a systematic review and meta-analysis.

AIDS research and therapy - 6 Jun 2024

Rachman Brian Eka, Khairunisa Siti Qamariyah, Wungu Citrawati Dyah Kencono, Asmarawati Tri Pudy, Rusli Musofa, Bramantono, Arfijanto M Vitanata, Hadi Usman, Kameoka Masanori, Nasronudin

Abstract excerpt

INTRODUCTION: Despite the widespread use of pre-exposure prophylaxis (PrEP) in preventing human immunodeficiency virus (HIV) transmission, scant information on HIV drug resistance mutations (DRMs) has been gathered over the past decade. This review aimed to estimate the pooled prevalence of pre-exposure prophylaxis and its two-way impact on DRM. METHODS: We systematically reviewed studies on DRM in pre-exposure...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38844950
DOI: 10.1186/s12981-024-00627-2
PMCID: PMC11155065

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