Article
The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis.
The European respiratory journal - 1 Nov 2018
Miller Suzanne, Coveney Clare, Johnson Janice, Farmaki Aliki-Eleni, Gupta Nishant, Tobin Martin D, Wain Louise V, McCormack Francis X, Boocock David J, Johnson Simon R
Abstract excerpt
Lymphangioleiomyomatosis (LAM) is a rare disease of women. Decline in lung function is variable, making appropriate targeting of therapy difficult. We used unbiased serum proteomics to identify markers associated with outcome in LAM.101 women with LAM and 22 healthy controls were recruited from the National Centre for LAM in the UK. 152 DNA and serum samples with linked lung function and outcome data were...
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