Article
The Proteomic Profile of Interstitial Lung Abnormalities.
American journal of respiratory and critical care medicine - 1 Aug 2022
Axelsson Gisli Thor, Gudmundsson Gunnar, Pratte Katherine A, Aspelund Thor, Putman Rachel K, Sanders Jason L, Gudmundsson Elias F, Hatabu Hiroto, Gudmundsdottir Valborg, Gudjonsson Alexander, Hino Takuya, Hida Tomoyuki, Hobbs Brian D, Cho Michael H, Silverman Edwin K, Bowler Russell P, Launer Lenore J, Jennings Lori L, Hunninghake Gary M, Emilsson Valur, Gudnason Vilmundur
Abstract excerpt
Rationale: Knowledge on biomarkers of interstitial lung disease is incomplete. Interstitial lung abnormalities (ILAs) are radiologic changes that may present in its early stages. Objectives: To uncover blood proteins associated with ILAs using large-scale proteomics methods. Methods: Data from two prospective cohort studies, the AGES-Reykjavik (Age, Gene/Environment Susceptibility-Reykjavik) study (N = 5,259) for...
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