Article
Whole genome analyses of CMY-2-producing Escherichia coli isolates from humans, animals and food in Germany.
BMC genomics - 9 Aug 2018
Pietsch Michael, Irrgang Alexandra, Roschanski Nicole, Brenner Michael Geovana, Hamprecht Axel, Rieber Heime, Käsbohrer Annemarie, Schwarz Stefan, Rösler Uwe, Kreienbrock Lothar, Pfeifer Yvonne, Fuchs Stephan, Werner Guido
Abstract excerpt
BACKGROUND: Resistance to 3rd-generation cephalosporins in Escherichia coli is mostly mediated by extended-spectrum beta-lactamases (ESBLs) or AmpC beta-lactamases. Besides overexpression of the species-specific chromosomal ampC gene, acquisition of plasmid-encoded ampC genes, e.g. blaCMY-2, has been described worldwide in E. coli from humans and animals. To investigate a possible transmission of blaCMY-2 along...
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