Article
Gene editing in the context of an increasingly complex genome.
BMC genomics - 8 Aug 2018
Blighe K, DeDionisio L, Christie K A, Chawes B, Shareef S, Kakouli-Duarte T, Chao-Shern C, Harding V, Kelly R S, Castellano L, Stebbing J, Lasky-Su J A, Nesbit M A, Moore C B T
Abstract excerpt
The reporting of the first draft of the human genome in 2000 brought with it much hope for the future in what was felt as a paradigm shift toward improved health outcomes. Indeed, we have now mapped the majority of variation across human populations with landmark projects such as 1000 Genomes; in cancer, we have catalogued mutations across the primary carcinomas; whilst, for other diseases, we have identified the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.