Historical control data on developmental toxicity studies in rats.

doi:10.1111/cga.12305

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Article

Historical control data on developmental toxicity studies in rats.

Congenital anomalies - 1 Jul 2019

Kuwagata Makiko, Sakai Yuko, Tanaka Sho, Takashima Hiromasa, Katagiri Ryuichi, Matsuoka Toshiki, Noritake Kenichi, Senuma Mika, Shimizu Tatsuya, Hojo Hitoshi, Ibi Kanata, Kudo Satoshi, Oota Takafumi, Ube Masayuki, Miwa Yoji, Kajita Shimpei, Uesugi Tohru, Yabe Kaoru, Tateishi Taishi, Nakano Nao, Taniguchi Terumasa, Yamashita Akihito, Hirano Takayuki, Kirihata Yuka, Sakai Yumi, Nishizawa Shino, Fujiwara Michio, Mineshima Hiroshi, Horimoto Masao, Ema Makoto

Abstract excerpt

Historical control data from prenatal developmental toxicity studies in rats have been used to evaluate whether toxicology outcomes were induced by exposure to a chemical or were within the range of spontaneous variation. These data are also important for monitoring animal characteristics. As a follow-up to historical control data from 1998 to 2010, this study analyzed control data from prenatal developmental...

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PMID: 30084506
DOI: 10.1111/cga.12305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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