Article
Unravelling the history of hepatitis B virus genotypes A and D infection using a full-genome phylogenetic and phylogeographic approach.
eLife - 7 Aug 2018
Kostaki Evangelia-Georgia, Karamitros Timokratis, Stefanou Garyfallia, Mamais Ioannis, Angelis Konstantinos, Hatzakis Angelos, Kramvis Anna, Paraskevis Dimitrios
Abstract excerpt
Hepatitis B virus (HBV) infection constitutes a global public health problem. In order to establish how HBV was disseminated across different geographic regions, we estimated the levels of regional clustering for genotypes D and A. We used 916 HBV-D and 493 HBV-A full-length sequences to reconstruct their global phylogeny. Phylogeographic analysis was conducted by the reconstruction of ancestral states using the...
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