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Article

Polygenic differential susceptibility to prenatal adversity.

Development and psychopathology - 1 May 2019

Belsky Jay, Pokhvisneva Irina, Rema Anu Sathyan Sathyapalan, Broekman Birit F P, Pluess Michael, O'Donnell Kieran J, Meaney Michael J, Silveira Patrícia P

Abstract excerpt

A recent article in this journal reported a number of gene × environment interactions involving a serotonin transporter-gene network polygenic score and a composite index of prenatal adversity predicting several problem behavior outcomes at 48 months (e.g., anxious/depressed, pervasive developmental problems) and at 60 months (e.g., withdrawal, internalizing problems), yet did not illuminate the nature or form...

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Identifiers

PMID: 30081968
DOI: 10.1017/S0954579418000378

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