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Article

Baldspot/ELOVL6 is a conserved modifier of disease and the ER stress response.

PLoS genetics - 1 Aug 2018

Palu Rebecca A S, Chow Clement Y

Abstract excerpt

Endoplasmic reticulum (ER) stress is an important modifier of human disease. Genetic variation in response genes is linked to inter-individual differences in the ER stress response. However, the mechanisms and pathways by which genetic modifiers are acting on the ER stress response remain unclear. In this study, we characterize the role of the long chain fatty acid elongase Baldspot (ELOVL6) in modifying the ER...

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Identifiers

PMID: 30081392
DOI: 10.1371/journal.pgen.1007557
PMCID: PMC6078684

Genes

ELOVL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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