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Article

The distinct role and regulatory mechanism of IL-17 and IFN-γ in the initiation and development of plaque vs guttate psoriasis.

Journal of dermatological science - 1 Oct 2018

Yan Kexiang, Han Ling, Deng Hui, Fang Xu, Zhang Zhenghua, Huang Guiqin, Zheng Zhi Zhong, Huang Qiong, Xu Jinhua

Abstract excerpt

BACKGROUND: Few studies have explored the differences of immunopathogenesis in plaque vs guttate psoriasis, especially on the inhibitory role of regulatory T cells (Tregs) on IL-17/ IFN-γ production and the impact of CD4+T cells on keratinocytes. OBJECTIVE: To investigate the percentage and inhibitory function of CD4+CD25highTreg and differential expressions of IL-17/ IFN-γ in plaque vs guttate psoriasis, and the...

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Identifiers

PMID: 30072243
DOI: 10.1016/j.jdermsci.2018.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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