Article
Activity of imipenem/relebactam against Pseudomonas aeruginosa with antimicrobial-resistant phenotypes from seven global regions: SMART 2015-2016.
Journal of global antimicrobial resistance - 1 Dec 2018
Karlowsky James A, Lob Sibylle H, Young Katherine, Motyl Mary R, Sahm Daniel F
Abstract excerpt
OBJECTIVES: Relebactam inhibits Ambler class A and C β-lactamases. Imipenem/relebactam has completed one phase 3 clinical study of patients infected with imipenem-non-susceptible Gram-negative bacilli. Two more phase 3 clinical studies are in progress for the treatment of patients with hospital-acquired and ventilator-associated bacterial pneumonia, complicated intra-abdominal infections and complicated urinary...
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