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Article

Pluripotent stem cell replacement approaches to treat type 1 diabetes.

Current opinion in pharmacology - 1 Dec 2018

Pellegrini Silvia, Piemonti Lorenzo, Sordi Valeria

Abstract excerpt

Stem cells represent a potential candidate for β cell replacement in type 1 diabetes. Pluripotent stem cells are able to differentiate in vitro into functional insulin producing cells, that can restore normoglycemia in diabetic mice. Clinical trials with embryonic stem cell-derived pancreatic progenitors are ongoing. Besides, induced pluripotent stem cells offer the chance of personalized cell therapy. So far,...

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Identifiers

PMID: 30071348
DOI: 10.1016/j.coph.2018.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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