Article
Mendelian randomisation analysis of clustered causal effects of body mass on cardiometabolic biomarkers.
BMC bioinformatics - 9 Jul 2018
Conde Susana, Xu Xiaoguang, Guo Hui, Perola Markus, Fazia Teresa, Bernardinelli Luisa, Berzuini Carlo
Abstract excerpt
BACKGROUND: Recent advances in data analysis methods based on principles of Mendelian Randomisation, such as Egger regression and the weighted median estimator, add to the researcher's ability to infer cause-effect links from observational data. Now is the time to gauge the potential of these methods within specific areas of biomedical research. In this paper, we choose a study in metabolomics as an illustrative...
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