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Copper sensing transcription factor ArsR2 regulates VjbR to sustain virulence in Brucella abortus

19 Sept 2024

Abstract excerpt

Brucellosis, caused by the intracellular pathogen Brucella, is a major zoonotic infection that promotes reproductive disease in domestic animals and chronic debilitating conditions in humans. The ArsR family of transcriptional regulators plays key roles in diverse cellular processes, including metal ion homeostasis, responding to adverse conditions, and virulence. However, little is known about the function of...

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PMID: 39295505
DOI: 10.1080/22221751.2024.2406274

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