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Article

Evaluation and validation of HPV real-time PCR assay for the detection of HPV DNA in oral cytobrush and FFPE samples.

Scientific reports - 27 Jul 2018

Harlé Alexandre, Guillet Julie, Thomas Jacques, Sastre-Garau Xavier, Rouyer Marie, Ramacci Carole, Gilson Pauline, Dubois Cindy, Dolivet Gilles, Leroux Agnès, Salleron Julia, Merlin Jean-Louis

Abstract excerpt

Specific HPV genotypes have been recognized as risk factors inducing head and neck cancers (HNC). The aim of this study was to validate a real-time PCR assay to detect accurately High Risk HPV DNA in Formalin Fixed Paraffin Embedded (FFPE) and oral cytobrush samples and compare the results with conventional PCR. Repeatability, reproducibility and limit of detection of Cobas assay were estimated for oral cytobrush...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30054550
DOI: 10.1038/s41598-018-29790-z
PMCID: PMC6063863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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