Article
High-risk Human Papillomavirus Determination in Formalin-fixed, Paraffin-embedded Cervical Tissue Using the Roche Cobas 4800 System: A Comparative Study With Liquid-based Cytology.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2019
Tardío Juan C, Cambero Olivia, Sánchez-Estévez Carolina, Sánchez-García Ana B, Angulo Fernando, Moreno Amalia
Abstract excerpt
Roche cobas 4800 human papillomavirus (HPV) test is an automated real-time polymerase chain reaction-based system that allows the simultaneous detection of 14 human papillomavirus high-risk (HR-HPV) genotypes. This test is Food and Drug Administration approved since 2011 for HPV determination in liquid-based cytologic samples, but a clinically validated technique for formalin-fixed, paraffin-embedded (FFPE)...
Topics
- Biopsy
- Carcinoma, Squamous Cell
- Cervix Uteri
- Female
- Formaldehyde
- Genotype
- Humans
- Papillomaviridae
- Papillomavirus Infections
- Paraffin Embedding
- Real-Time Polymerase Chain Reaction
- Retrospective Studies