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Article

Donor's APOL1 Risk Genotype and "Second Hits" Associated With De Novo Collapsing Glomerulopathy in Deceased Donor Kidney Transplant Recipients: A Report of 5 Cases.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jan 2019

Chang Jae-Hyung, Husain S Ali, Santoriello Dominick, Stokes Michael B, Miles Clifford D, Foster Kirk W, Li Yifu, Dale Leigh-Anne, Crew Russell J, Cohen David J, Kiryluk Krzysztof, Gharavi Ali G, Mohan Sumit

Abstract excerpt

The presence of 2 APOL1 risk variants (G1/G1, G1/G2, or G2/G2) is an important predictor of focal segmental glomerulosclerosis (FSGS) and chronic kidney disease in individuals of African descent. Although recipient APOL1 genotype is not associated with allograft survival, kidneys from deceased African American donors with 2 APOL1 risk variants demonstrate shorter graft survival. We present a series of cases of...

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Share to Apolipoprotein L1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulosclerosis, Focal Segmental

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Source

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Identifiers

PMID: 30054024
DOI: 10.1053/j.ajkd.2018.05.008
PMCID: PMC6309648

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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