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Article

Clinical and molecular features of X-linked hyper IgM syndrome - An experience from North India.

Clinical immunology (Orlando, Fla.) - 1 Oct 2018

Rawat Amit, Mathew Babu, Pandiarajan Vignesh, Jindal Ankur, Sharma Madhubala, Suri Deepti, Gupta Anju, Goel Shubham, Karim Adil, Saikia Biman, Minz Ranjana W, Imai Kohsuke, Nonoyama Shigeaki, Ohara Osamu, Giliani Silvia Clara, Notarangelo Luigi D, Chan Koon-Wing, Lau Yu-Lung, Singh Surjit

Abstract excerpt

X-linked hyper IgM Syndrome (XLHIGM), the most frequent form of the Hyper IgM syndromes is a primary immune deficiency resulting from a mutation in the CD40 ligand gene (CD40LG). We analyzed the clinical and laboratory features of ten patients with XLHIGM, who were diagnosed at a tertiary care hospital in North India. Most common infections were sinopulmonary infections (80%) and diarrhea (50%). Sclerosing...

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Identifiers

PMID: 30053428
DOI: 10.1016/j.clim.2018.07.013
PMCID: PMC6666391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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