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Article

Clinical features and genetic analysis of 20 Chinese patients with X-linked hyper-IgM syndrome.

Journal of immunology research - 1 Jan 2014

Wang Lin-Lin, Zhou Wei, Zhao Wei, Tian Zhi-Qing, Wang Wei-Fan, Wang Xiao-Fang, Chen Tong-Xin

Abstract excerpt

X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and followed up in hospitals affiliated to Shanghai Jiao Tong University School of Medicine from 1999 to 2013. The median onset age of these patients was 8.5 months...

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Identifiers

PMID: 25215306
DOI: 10.1155/2014/683160
PMCID: PMC4158165

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Source receipt: pubmed, retrieved 7 Sept 2026.

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