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Article

Value of HPV 16/18 Genotyping and p16/Ki-67 Dual Staining to Predict Progression to HSIL/CIN2+ in Negative Cytologies From a Colposcopy Referral Population.

American journal of clinical pathology - 1 Oct 2018

Rodríguez-Trujillo Adriano, Martí Cristina, Angeles Martina Aida, Sierra Adriana, Esteve Roser, Saco Adela, Barnadas Esther, Marimón Lorena, Nicolás Inmaculada, Torné Aureli, Ordi Jaume, Del Pino Marta

Abstract excerpt

OBJECTIVES: To assess the prognostic value of human papillomavirus (HPV) 16/18 genotyping and p16/Ki-67 dual staining cytology in high-risk HPV (hrHPV)-positive women with no lesion or minor abnormalities. METHODS: We evaluated progression to high-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grades 2 to 3 or cervical cancer (HSIL/CIN2+), persistence/regression of hrHPV infection in...

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PMID: 30052715
DOI: 10.1093/ajcp/aqy071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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