Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced caudate volume and cognitive slowing in men at risk of fragile X-associated tremor ataxia syndrome.

Brain imaging and behavior - 1 Aug 2019

Cvejic Rachael C, Hocking Darren R, Wen Wei, Georgiou-Karistianis Nellie, Cornish Kim M, Godler David E, Rogers Carolyn, Trollor Julian N

Abstract excerpt

Fragile X-associated tremor ataxia syndrome is an inherited neurodegenerative disorder caused by premutation expansions (55-200 CGG repeats) of the FMR1 gene. There is accumulating evidence to suggest that early cognitive and brain imaging signs may be observed in some premutation carriers without motor signs of FXTAS, but few studies have examined the relationships between subcortical brain volumes and cognitive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia
Share to Caudate Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Executive Function

Share to Fragile X Mental Retardation Protein

Share to Fragile X Syndrome

Share to Memory, Short-Term

Share to Tremor

Share to Trinucleotide Repeat Expansion

Source

Identifiers

PMID: 30046972
DOI: 10.1007/s11682-018-9928-7

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced caudate volume and cognitive slowing in men at risk of fragile X-associated tremor ataxia syndrome.PMID 30046972Read ↗

Understanding the neuropsychiatric phenotype of fragile X-associated tremor ataxia syndrome: a systematic review.Semantic proximity Read ↗

Investigation of memory, executive functions, and anatomic correlates in asymptomatic FMR1 premutation carriers.Semantic proximity Read ↗

Selective executive markers of at-risk profiles associated with the fragile X premutation.Semantic proximity Read ↗

Selective spatial processing deficits in an at-risk subgroup of the fragile X premutation.Semantic proximity Read ↗

Brain structure in asymptomatic FMR1 premutation carriers at risk for fragile X-associated tremor/ataxia syndrome.Semantic proximity Read ↗

Neuropsychological findings from older premutation carrier males and their noncarrier siblings from families with fragile X syndrome.Semantic proximity Read ↗

Women with Fragile X–associated Tremor/Ataxia SyndromeSemantic proximity Read ↗

Fragile X premutation carriers: A systematic review of neuroimaging findings.Semantic proximity Read ↗

Relationships between motor scores and cognitive functioning in FMR1 female premutation X carriers indicate early involvement of cerebello-cerebral pathwaysSemantic proximity Read ↗

An fMRI study of the prefrontal activity during the performance of a working memory task in premutation carriers of the fragile X mental retardation 1 gene with and without fragile X-associated tremor/ataxia syndrome (FXTAS).Semantic proximity Read ↗

The apolipoprotein gene: a modulating role on brain volume and cognitive function in carriers of the fragile X premutation.Semantic proximity Read ↗

Age-dependent cognitive changes in carriers of the fragile X syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.