Article
[Vitamin D receptor polymorphism in the group of postmenopausal women with low bone mineral density].
Ginekologia polska - 1 May 2004
Seremak-Mrozikiewicz Agnieszka, Drews Krzysztof, Dańska Anna, Spaczyński Marek, Opala Tomasz, Mrozikiewicz Przemysław M
Abstract excerpt
OBJECTIVES: Osteoporosis is a multifactoral disease with aetiology depending from the hormonal, environmental, and genetic factors. One of the suggested candidate gene involved in the pathogenesis is the polymorphic gene encoding for vitamin D receptor (VDR). VDR polymorphism was connected with bone mineral density (BMD) and correlated with onset of osteoporosis. The goal of our study was to determine the role of...
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