Article
Vitamin D receptor polymorphisms and diseases.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2006
Valdivielso Jose M, Fernandez Elvira
Abstract excerpt
The vitamin D endocrine system is central to the control of bone and calcium homeostasis. Thus, alterations in the vitamin D pathway lead to disturbances in mineral metabolism. Furthermore, a role for vitamin D has been suggested in other diseases, like cancer, diabetes and cardiovascular disease. Expression and nuclear activation of the vitamin D receptor (VDR) are necessary for the effects of vitamin D. Several...
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