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Article

Severe BCG-osis Misdiagnosed as Multidrug-Resistant Tuberculosis in an IL-12Rβ1-Deficient Peruvian Girl.

Journal of clinical immunology - 1 Aug 2018

Esteve-Sole Ana, Sánchez-Dávila Suly P, Deyà-Martínez Angela, Freeman Alexandra F, Zelazny Adrian M, Dekker John P, Khil Pavel P, Holland Steven M, Noguera-Julian Antoni, Bustamante Jacinta, Casanova Jean-Laurent, Juan Manel, Cordova Wilmer, Alsina Laia

Abstract excerpt

PURPOSE: Mendelian suceptibility to mycobacterial disease (MSMD) is a rare primary immunodeficiency predisposing to severe disease caused by mycobacteria and other intracellular pathogens. Delay in diagnosis can have an impact on the patient's prognosis. METHODS: We evaluated the IFN-γ circuit by studying IFN-γ production after mycobacterial challenge as well as IL-12Rβ1 expression and STAT4 phosphorylation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30039354
DOI: 10.1007/s10875-018-0535-6

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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