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Investigation on modulation of DNA repair pathways in Chinese MJD patients.

Neurobiology of aging - 1 Nov 2018

Wang Chunrong, Chen Zhao, Peng Huirong, Peng Yun, Zhou Xin, Yang Huihua, Wang Puzhi, Li Tianjiao, Hou Xiaocan, Qiu Rong, Xia Kun, Sequeiros Jorge, Tang Beisha, Jiang Hong

Abstract excerpt

It has been reported that DNA repair pathways could modify age at onset (AO) in Huntington disease (HD) and spinocerebellar ataxias. We genotyped 22 SNPs from DNA repair pathways in a large cohort of 798 Chinese Machado-Joseph disease patients to investigate the association with AO, and no significant finding was observed. Our findings did not provide a strong evidence for the modulatory effect of DNA repair...

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Identifiers

PMID: 30033072
DOI: 10.1016/j.neurobiolaging.2018.06.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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