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Article

Monitoring Viral Genetic Variation as a Tool To Improve Molecular Diagnostics for Mumps Virus.

Journal of clinical microbiology - 1 Oct 2018

Dilcher Meik, Barratt Kevin, Douglas Jennifer, Strathdee Andrew, Anderson Trevor, Werno Anja

Abstract excerpt

Here, we report how the analysis of viral genetic variation using next-generation sequencing (NGS) can be used as a tool to improve mumps virus diagnostics. Analysis of NGS data from recently circulating mumps virus isolates allowed optimization of the current mumps virus real-time reverse transcription-PCR (RT-PCR) by primer and probe modifications due to nucleotide variations. The modified assay showed a higher...

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Identifiers

PMID: 30021826
DOI: 10.1128/JCM.00405-18
PMCID: PMC6156297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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