Combining genomics and epidemiology to track mumps virus transmission in the United States.

doi:10.1371/journal.pbio.3000611

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Article

Combining genomics and epidemiology to track mumps virus transmission in the United States.

PLoS biology - 1 Feb 2020

Wohl Shirlee, Metsky Hayden C, Schaffner Stephen F, Piantadosi Anne, Burns Meagan, Lewnard Joseph A, Chak Bridget, Krasilnikova Lydia A, Siddle Katherine J, Matranga Christian B, Bankamp Bettina, Hennigan Scott, Sabina Brandon, Byrne Elizabeth H, McNall Rebecca J, Shah Rickey R, Qu James, Park Daniel J, Gharib Soheyla, Fitzgerald Susan, Barreira Paul, Fleming Stephen, Lett Susan, Rota Paul A, Madoff Lawrence C, Yozwiak Nathan L, MacInnis Bronwyn L, Smole Sandra, Grad Yonatan H, Sabeti Pardis C

Abstract excerpt

Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks. We paired epidemiological data from public health investigations with analysis of mumps virus whole genome sequences from 201 infected individuals, focusing on Massachusetts university communities. Our analysis suggests...

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PMID: 32045407
DOI: 10.1371/journal.pbio.3000611
PMCID: PMC7012397

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