Article
Evaluation of the genomic diversity of viruses infecting bacteria, archaea and eukaryotes using a common bioinformatic platform: steps towards a unified taxonomy.
The Journal of general virology - 1 Sept 2018
Aiewsakun Pakorn, Adriaenssens Evelien M, Lavigne Rob, Kropinski Andrew M, Simmonds Peter
Abstract excerpt
Genome Relationship Applied to Virus Taxonomy (GRAViTy) is a genetics-based tool that computes sequence relatedness between viruses. Composite generalized Jaccard (CGJ) distances combine measures of homology between encoded viral genes and similarities in genome organizational features (gene orders and orientations). This scoring framework effectively recapitulates the current, largely morphology and...
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