Article
Unveiling the cryptic diversity and distribution of elements related to virophage mavirus through deep mining of pPolB proteins.
Virologica Sinica - 1 Apr 2026
Wei Yutong, Liu Qiyan, Gong Zhen, Han Guan-Zhu
Abstract excerpt
Virophages are unique double-stranded DNA (dsDNA) viruses that parasitize viruses of Nucleocytoviricota (NCVs). While conventionally viewed as a viral group, growing evidence suggests that "virophage" is better understood as a parasitic lifestyle, rather than a natural group. Despite this conceptual shift, their diversity and evolution remain largely obscure and contentious. Through deep mining of protein-primed...
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